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AbbVie Senior Scientist, I in Worcester, Massachusetts

Senior Scientist, I

USA, Massachusetts, Worcester

1 additional location

USA, Massachusetts

Research & Development

Requisition # 1906686

The Bioanalytical team at AbbVie in Worcester, MA is seeking a creative, experienced, and highly motivated scientist to develop and implement bioanalytical biomarker methods to support the discovery and development of novel therapies in multiple therapeutic areas. The ideal candidate will support local Immunology discovery projects with ligand binding methods, ex-vivo stimulation parameter optimization, pre-analytics (sample processing steps); and be key member of a global biomarker bioanalysis team supporting all AbbVie therapeutic areas with fit-for-purpose methods to enable discovery and development stage decision making.


  • Develop, validate, transfer, and troubleshoot robust ligand binding biomarker assays on multiple analytical platforms across a variety of sample matrices

  • Conduct and document appropriately compliant biomarker sample testing to support non-clinical and clinical studies

  • Develop effective partnerships with discovery, preclinical safety, clinical pharmacology, and project team representatives in a culture of collaboration and innovation to deliver timely data of high impact

  • Evaluate novel, pipeline-enabling, assay technologies to expand capabilities and enhance efficiency

  • Prepare presentations and effectively communicate scientific progress to line management and internal stakeholder groups

  • Actively participates in knowledge sharing, harmonizing best practices, and capacity management across the global biomarker bioanalysis team at AbbVie

  • Maintain laboratory notebooks in compliance with AbbVie policies

Key Stakeholders: AbbVie Discovery scientists, bioanalytical colleagues, project team representatives, and DMPK-BA leadership


  • Bachelor’s Degree in Chemistry, Biology, Immunology or related field and a minimum of 10 years of experience or 8 years of experience with Master degree or PhD and no experience.

  • In-depth knowledge of LBA biomarker bioanalytical assay development, validation practices, and sample testing workflows to comply with current regulatory standards and best industry practices

  • Proficient in multiple analytical platforms, including ELISA, MSD, ex-vivo stimulation pre-analytics, and emerging technologies

  • Familiarity with PK/TK and immunogenicity bioanalytical method development approaches

  • Working knowledge of Good Laboratory Practices (GLP), Good Clinical Practices (GCP), and GCLP compliance models is a plus.

  • Excellent communication skills, proven ability to work effectively as a member of a multidisciplinary team, and the ability to summarize data clearly and thoroughly in one-on-one, group, and global meetings

  • Demonstrated capacity to work in a fast-paced environment with meticulous attention to detail, and an ability to handle multiple projects, prioritize work, and meet deadlines

  • Experiences with Simoa or other ultra-sensitive platforms is a plus.

Additional Information

  • Significant Work Activities and Conditions: N/A

  • Travel: Yes, 5 % of the Time

  • Job Type: Experienced

  • Schedule: Full-time

Equal Employment Opportunity Employer

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.