AbbVie Scientist, Immunology - Immune Cell Signaling & Molecular Biology in Worcester, Massachusetts

Scientist, Immunology - Immune Cell Signaling & Molecular Biology

New

USA, Massachusetts, Worcester

1 additional location

USA, Massachusetts

Research & Development

Requisition #1808761

We are seeking a highly motivated and creative scientist with background in Immunology, immune cell signaling and molecular biology to join the AbbVie Global Biologics Discovery organization in Worcester, MA. This individual will work in drug discovery cross-functional teams both internally and externally to characterize and test recombinant proteins for different therapeutic areas including Immunology, Neuroimmunology and Immuno-oncology.

Responsibilities:

  • Perform mammaliancell culture and independently develop, run, analyze and troubleshoot in vitroassays, such as ELISA, western blot, FACs & cell-based activity assays.

  • Use developed invitro assays to validate and characterize novel therapeutic proteins

  • Demonstrateinnovation and strong problem solving, analytical skills and be a team player.

  • Work collaboratively with matrixed project teams and members of theGlobal Biologics Group to drive innovation and deliver novel therapies forpatients

  • Develop productive collaborations and communication with othergroups across therapeutic areas

  • Timely documentation of experiments andactivities in electronic archive systems

  • Engage colleagues in cross-disciplinaryscientific discussion, present scientific data to internal and externalaudiences and publish research in peer-reviewed journals

Position will be hired based on level of experience.

  • BS in Immunology, molecular biology, or related field with at 5-7+ years of relevant experience or MS with 2-5+ years of experience

  • Extensive expertise in mammalian cell culture/transfection and in vitro analytical techniques for protein characterization (such as ELISA, western blot, FACs & cell-based activity assays) is required

  • Experienced in cell isolation and culture of primary immune cells (dendritic cells, macrophages and T cells) is required

  • Proficiency in a wide range of molecular biology and immunology techniques (Molecular cloning, RNA isolation, c-DNA synthesis, qPCR, proliferation/cytotoxicity assays)

  • Experience in extracellular matrix biology in mammalian systems is a plus

  • Experience with in vivo rodent models (IBD, CIA, xenograft) is a plus

  • Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions

Equal Opportunity Employer Minorities/Women/Veterans/Disabled

Additional Information

  • Travel: No

  • Job Type: Experienced

  • Schedule: Full-time