AbbVie Associate Scientist I/II, Protein Engineering & Characterization in Worcester, Massachusetts
Associate Scientist I/II, Protein Engineering & Characterization
USA, Massachusetts, Worcester
Research & Development
We are seeking a highly motivated and creative scientist with a background in protein engineering, expression, purification and analytical characterization to join the AbbVie Global Biologics Discovery organization. This individual will work in drug discovery cross-functional teams both internally and externally to design, produce, characterize and test recombinant proteins for different therapeutic areas including metabolic diseases, oncology, immunology and aging.
Execute hands on scientific research involving engineering, production and screening of recombinant tool and therapeutic proteins, including antigens, antibodies, fusion proteins and multi-specific biologics.
Apply various protein analytical methods to characterize and test recombinant proteins in relevant biochemical and cellular experiments.
Work collaboratively with matrixed project teams and members of the Global Biologics Group to drive innovation and deliver novel therapies for patients.
Develop productive collaborations and communication with other groups across therapeutic areas.
Timely documentation of experiments and activities in electronic archive systems.
Engage colleagues in cross-disciplinary scientific discussion, present scientific data to internal and external audiences and publish research in peer-reviewed journals.
Position will be hired based on level of experience.
Bachelors or Masters degree in biochemistry or related discipline
Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions.
Expertise in recombinant protein production, proficiency in analytical techniques for protein characterization (such as mass spectrometry, chromatography and others).
Hands-on experience in molecular cloning, and designing/producing novel bi-specific proteins in mammalian and bacterial cells, is highly desired.
Proficiency in biochemical assay development including MSD, ForteBio, and receptor ligand interaction assays.
Familiarity with molecular modeling.
Experience in biochemistry and cellular biology of metalloproteinases.
Significant Work Activities and Conditions: N/A
Job Type: Experienced
Job Level Code: IC