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AbbVie Associate Scientist I/II, Protein Engineering & Characterization in Worcester, Massachusetts

Associate Scientist I/II, Protein Engineering & Characterization

USA, Massachusetts, Worcester

Research & Development

Requisition #2002126

We are seeking a highly motivated and creative scientist with a background in protein engineering, expression, purification and analytical characterization to join the AbbVie Global Biologics Discovery organization. This individual will work in drug discovery cross-functional teams both internally and externally to design, produce, characterize and test recombinant proteins for different therapeutic areas including metabolic diseases, oncology, immunology and aging.

Responsibilities :

  • Execute hands on scientific research involving engineering, production and screening of recombinant tool and therapeutic proteins, including antigens, antibodies, fusion proteins and multi-specific biologics.

  • Apply various protein analytical methods to characterize and test recombinant proteins in relevant biochemical and cellular experiments.

  • Work collaboratively with matrixed project teams and members of the Global Biologics Group to drive innovation and deliver novel therapies for patients.

  • Develop productive collaborations and communication with other groups across therapeutic areas.

  • Timely documentation of experiments and activities in electronic archive systems.

  • Engage colleagues in cross-disciplinary scientific discussion, present scientific data to internal and external audiences and publish research in peer-reviewed journals.

Position will be hired based on level of experience.

  • Bachelors or Masters degree in biochemistry or related discipline

  • Strong communication and organization skills, especially the ability to work across multiple scientific disciplines and functions.

Preferred Experience:

  • Expertise in recombinant protein production, proficiency in analytical techniques for protein characterization (such as mass spectrometry, chromatography and others).

  • Hands-on experience in molecular cloning, and designing/producing novel bi-specific proteins in mammalian and bacterial cells, is highly desired.

  • Proficiency in biochemical assay development including MSD, ForteBio, and receptor ligand interaction assays.

  • Familiarity with molecular modeling.

  • Experience in biochemistry and cellular biology of metalloproteinases.

Additional Information

  • Significant Work Activities and Conditions: N/A

  • Travel: No

  • Job Type: Experienced

  • Schedule: Full-time

  • Job Level Code: IC

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