AbbVie Associate Scientist II/Scientist I, Cancer Biology in South San Francisco, California

Associate Scientist II/Scientist I, Cancer Biology

USA, California, South San Francisco

Research & Development

Requisition #1806917

Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products — Imbruvica, Venclexta, and Empliciti — and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer.

AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, statisticians, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments. This position will be based at Stemcentrx, AbbVie’s South San Francisco oncology site.

AbbVie Stemcentrx in South San Francisco is comprised of a multi-disciplinary team of world-class scientists is developing novel targeted therapeutics in oncology, with a specific focus on antibody-drug conjugates and other antibody-based approaches. We are looking for an Associate Scientist / Scientist with experience in cell culture, tissue processing, flow cytometry, as well as standard molecular biology and biochemical techniques. Above all, we are looking for a highly motivated and collaborative individual with a passion for oncology research, who enjoys working in a fast-paced and highly dynamic working environment.

Responsibilities:

  • Manage and expand PDX bank and cell line collection

  • Test novel drugs with a combination of in vitro and in vivo assays

  • Perform daily FACS-based analysis of PDX tumors

  • Perform cell-based or biochemical assays on a tight schedule

  • Maintain flow cytometers

  • Analyze and report data regularly at group meetings

Basic :

  • BS degree and 4+ years or MS degree and 2+ years of relevant experience.

  • Technical expertise in cell and molecular biology and/or cancer biology

  • Experience with mouse models of cancer, including PDX (Patient Derived Xenograft) models preferred

  • Experience working in an industry setting, specifically cancer biology, is preferred.

  • Excellent laboratory, record keeping, data analysis, and critical thinking skills.

  • Ability to plan, execute, and troubleshoot experiments.

  • Ability to manage more than one project at any given time and to work successfully in a cross-functional and highly collaborative team environment

  • Exceptional communication, both speech and writing, to a variety of audience types

  • Excellent working knowledge of Microsoft Word, Excel, PowerPoint, FlowJo and GraphPad Prism

Equal Opportunity Employer Minorities/Women/Veterans/Disabled