AbbVie Senior Scientist III, Chemical Engineering in North Chicago, Illinois

Senior Scientist III, Chemical Engineering

USA, Illinois, North Chicago

Research & Development

Requisition #1803917

Process Research and Development invents chemical processes and prepares active pharmaceutical ingredient (API) to enable clinical trials, toxicology studies and drug product development for AbbVie’s pre-clinical and clinical drug pipeline.

In addition to working with small molecules, Process R&D also develops antibody drug conjugates (ADC). We create valuable intellectual property through composition of matter, chemical processes and technologies resulting in cost effective commercial manufacturing processes. We develop the supply chain for APIs, prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content.

Chemical Engineers in AbbVie's R&D work in multi-functional teams to develop scalable processes and supply API for safety testing, clinical trials and formulation development. The teams include Process Chemistry, Pilot Plant Operations, Analytical Chemistry and Solid State Chemistry. Chemical Engineers support API projects through all phases of development. Early in development, engineers focus on ensuring the process can be run safely, identifying and addressing major scale-up issues and developing the final (API) process step.

Later in the development process, engineers optimize the API process and lead process campaigns run in the R&D Pilot Plant. In the final stage of development, engineers transfer the optimized process to manufacturing and support process validation.

Job Description:

The successful candidate will play a key role in the ProcessChemical Engineering function within Process R&D.

  • Develop robust commercial processes to manufacturesmall molecule APIs and ADCs.

  • Address challenging problems in chemical reactions,extractions, distillations, crystallizations, filtration and drying tomeet the target chemical and physical property attributes of the productthrough an in-depth scientific assessment of these unitprocesses/operations.

  • Expected to lead identification and development ofnovel approaches and technologies to enhance efficiency in process developmentand commercialization.

  • Must exhibit a collaborative nature in identifyingprocess challenges on a wide range of projects, and take on a leadershiprole in developing and implementing solutions.

Level and compensation will be commensuratewith experience.

Basic:

  • BS, MS, PhD in Chemical Engineering with 14+ (BS), 12+(MS), or 6+ (PhD) years of experience

  • Strong background in the design and development ofchemical engineering unit operations and processes.

  • Must possess at least 3 years of demonstratedpharmaceutical development experience and familiarity with various processanalytical technologies (PATs).

Key Leadership Competencies:

  • Builds strong relationships with peers and crossfunctionally with partners to enable higher performance.

  • Learns fast, grasps the "essence" and canchange course quickly where indicated.

  • Raises the bar and is never satisfied with the statusquo.

  • Creates a learning environment, open to suggestions andexperimentation for improvement.

  • Embraces the ideas of others, nurtures innovation andmanages innovation to reality.

  • Strong interpersonal and communication skills withdemonstrated ability to work within a team environment.

Equal Opportunity Employer Minorities/Women/Veterans/Disabled