AbbVie Senior Scientist II / Principal Scientist I, Process Chemistry in North Chicago, Illinois
Senior Scientist II / Principal Scientist I, Process Chemistry
USA, Illinois, Lake County
Research & Development
Following its separation from Abbott, AbbVie formed in 2013 and combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader. AbbVie employs approximately 29,000 people worldwide and markets medicines in more than 170 countries.
AbbVie is seeking a Senior Scientist II / Principal Scientist I to conduct process research and development of small molecules from pre-clinical through commercialization.We seek a highly motivated scientist, with a proven track record of accomplishment in the biopharmaceutical industry, to work in a multi-functional team environment. The qualified candidate will deliver results in a team-oriented setting.
The successful candidate will beresponsible for setting project strategies, defining projectresponsibilities and timelines, providing leadership in a matrixed teamsetting and developing robust processes for cGMP manufacturing of AbbVie’ssmall molecule and/or antibody-drug conjugate candidates.
Conceive of anddevelop synthetic routes for early-stage clinical deliveries, demonstrateprocesses in the API Pilot Plant, develop commercial manufacturingprocesses, establish commercial control strategies, and transfer theprocesses to commercial manufacturing sites.
The positioninvolves multi-disciplinary interactions with organic chemists, analyticalchemists, engineers, solid state scientists, drug product development,program management, etc.Theselected candidate will collaborate with Asset Development Teams toadvance clinical candidates. It is expected that the candidate willutilize his/her expertise across CMC disciplines to generatecollaborations with drug product development, regulatory affairs, andcommercial operations, to further program goals.
Serve as thelead author on development reports and as a key contributor to regulatoryfilings.
BS, MS, or PhD in chemistry and 12-14 (BS), 10-12 (MS), or 4-6 years (PhD) of relevant experience required. Candidates with less experience may be considered for other opportunities.
Proven scientific leadership and a demonstrated ability to lead cross-functional process development teams in a collaborative fashion.
The successful candidate will have a strong understanding of control strategy development, regulatory starting material strategies, specification setting, determining operating parameter ranges, QbD principles and process validation requirements.
An understanding of global regulatory expectations and experience with authoring development reports and regulatory filings is highly desirable.
The ideal candidate will have strong verbal and written communication skills
Key Leadership Competencies :
Buildsstrong relationships with peers and cross functionally with partnersoutside of team to enable higher performance.
Learnsfast, grasps the "essence" and can change course quickly whereindicated.
Raisesthe bar and is never satisfied with the status quo.
Createsa learning environment, open to suggestions and experimentation forimprovement.
Embracesthe ideas of others, nurtures innovation and manages innovation toreality.
Level and compensation will be commensurate with experience
Significant Work Activities and Conditions: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: Yes, 5 % of the Time
Job Type: Experienced
Job Level Code: IC