AbbVie Senior Scientist, Biochemistry - Targeted Protein Degradation in North Chicago, Illinois
Senior Scientist, Biochemistry - Targeted Protein Degradation
USA, Illinois, Lake County
Research & Development
We are seeking a highly-motivated biochemist, preferably with pharma/biotech experience, to join the Protein Degradation group in North Chicago, IL. This individual should have expertise in ubiquitin-related signaling or targeted protein degradation biology. A proven track record in successfully developing biochemical assays that probe this system is preferred. This individual should enjoy working with innovative technologies in a fast-paced environment.
Providing expertise in ubiquitin-related signaling and E3 ligase biology
Develop innovative strategies to study Protein Degrader engagement with the ubiquitin proteasome system
Developed robust in vitro profiling assays that support chemistry efforts in understanding structure-activity relationships
Apply novel techniques towards Protein Degrader drug discovery and elucidation of mechanism of action
Lead and interact with cross-functional scientific teams
Read and apply relevant scientific literature
Present research activities at internal and external meetings.
BS, MS, or PhD with 10+ (BS), 8+(MS), or 0+(PhD) in biochemistry, enzymology, chemical biology or related fields
Experience and publication track record in ubiquitin-proteasome system and/or targeted protein degradation biology
Proficient at developing enzyme activity assays and/or protein-protein interaction assays
Experience with molecular and cell biology techniques.
Experience analyzing data using statistical software programs such as GraphPad PRISM, Microsoft Excel, and Spotfire
Motivated, independent, and productive problem solver with a proven ability to advance new scientific understandings
Excellent verbal and non-verbal communication skills
Ability to work independently, yet works efficiently in teams to achieve objectives
Present research activities/results at internal and external meetings, and publish in peer-reviewed journals
Significant Work Activities and Conditions: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Job Type: Experienced
Job Level Code: M