AbbVie Scientist I/II, In Vivo in North Chicago, Illinois
Scientist I/II, In Vivo
USA, Illinois, North Chicago
2 additional locations
Research & Development
The Biotransformation group in DMPK-BA has an open position for an expert in conducting in vivo studies to support drug discovery and development. The selected candidate will be responsible for providing critical samples required to drive the pipeline and answer key scientific questions. The candidate will collaborate across various disciplines within AbbVie including DMPK, chemistry, biology, toxicology and pathology to support biotransformation and PK. The individual is expected to have a high level of practical experience performing in vivo studies, sample harvesting, sectioning tissues, managing radioactive compounds, and possess strong written and oral communication skills.
Care and handling of laboratory animals (rat,dog, mouse), including restraint, dosing, and minor surgical procedures
Necropsy and collection of tissues, blood andbile collection
Experimental design, conducting studies, andin vitro sample processing.
Familiarity with the IACUC and IACUCprotocols.Maintenance, training,renewal, and amendments as needed.
Familiarity with Culex operation and Debrasoftware.
Troubleshoot experiments and instrumentation.
Understand and adhere to corporate standardsregarding code of conduct, safety, appropriate handling of materials,controlled drug and radioactive compounds and animal care where applicable.
Level will be based on education & years of experience
Bachelor's Degree, Veterinary Technician certification, AALAScertification or equivalent education in a scientific discipline, withtypically 1-3+ or more years' experience.
Expert performing in vivostudies
Proficient with hepatocyteincubations
Oxidizer use and maintenance
Skilled with sectioning ofvarious tissues
Demonstrated expert in samplepreparation methods
Advanced training withradio-active material
Experience with liquidchromatography mass spectrometry platforms a plus
Strong interpersonal skills,the ability to work independently with minimal supervision inmanaging multiple projects and priorities and work well within a team
Strong presentation andwritten/verbal communication skills.
Builds strong relationshipswith peers and cross functionally with partners outside of team to enablehigher performance
Learns fast, grasps the'essence' and can change the course quickly where indicated
Raises the bar and is neversatisfied with the status quo
Creates a learning environment,open to suggestions and experimentation for improvement
Embraces the ideas of others,nurtures innovation and manages innovation to reality
Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Job Type: Experienced