AbbVie PostDoc New Chemical Entities Formulation Sciences Biopharmaceutical Method Development – temporary in Ludwigshafen, Germany
PostDoc New Chemical Entities Formulation Sciences Biopharmaceutical Method Development – temporary
Germany, Rhinland-Palatinate, Ludwigshafen
Research & Development
Research project: Opportunities of artificial gastrointestinal models in biopharmaceutical method development and its impact on oral drug formulation development
The Pharmaceutics Team within NCE Formulation Sciences department is seeking a motivated Post-Doctoral Fellow with a strong interest in better understanding the opportunities and limitations of available biopharmaceutic methods. Specifically, the selected candidate will be involved in:
Establishing new and improving existing biopharmaceutics methods to study the behavior of orally administered drugs in the GIT
Method development for analytical characterization of the samples processed by in vitro dissolution assays
Evaluation of physico-chemical characteristics of active pharmaceutical ingredients (API) and corresponding formulation prototypes in order to select the suitable bio relevant in vitro method
Comparison of in vitro data with in vivo data with regard to pharmacokinetic parameters
Process optimization in analytics and formulation development using Design of Experiments methodology
Drive innovative science, monitor or conduct experiments and studies, to advance projects or technologies
Supervision of students and pharmaceutics interns in scientific initiatives
Sharing information and presenting results in globally acting teams
Description of experiments, presentation and assessment of results in reports and publications as well as documentation of the gained knowledge in SOPs
Temporary position for 24 month.
PhD in natural sciences, preferably with a background in pharmacy, pharmacology, analytical chemistry, biochemistry, biology, biotechnology or related field
Demonstrated skills in analytical characterization of new chemical entities (especially drug release and HPLC/UPLC)
Experience with gastro-intestinal testing with the TNO gastroIntestinal Models (TIM) preferable
Strong knowledge in pharmacokinetics and pharmacodynamics methodologies
Knowledge in pharmaceutical technology and formulation
Ability to develop, design, execute and manage complex research programs
Proficient in data analysis, quantitative techniques
Strong analytical mind with good problem solving and writing skills
Fluent in English, German is a plus
Team player with excellent organizational and communication/presentation skills
Ability to interact and establish positive interaction with internal/external customers
Highly motivated and independent, organized and result-oriented
We are looking forward to your application. Please provide information about your salary expectations and possible start date in your motivation letter.
An equal opportunity employer. AbbVie welcomes and encourages diversity in our workforce.
Learn more about AbbVie Deutschland at www.abbvie.de Visit www.abbvie-care.de for more information about the therapeutic areas in which we’re active.