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AbbVie Post-Doctoral Research Scientist - Tau Biology, Neuroscience Discovery (m/w/d) in Ludwigshafen, Germany

Post-Doctoral Research Scientist - Tau Biology, Neuroscience Discovery (m/w/d)

Germany, Rhinland-Palatinate, Ludwigshafen

Research & Development

Requisition #1903372

The position is located within the Tau Biology Group in the Neuroscience Discovery organization at Ludwigshafen and will support a European Innovative Medicines Initiative (IMI) Project. The accomplished neurobiologist will make substantial contributions to the conception and execution of new therapeutic approaches to neurodegenerative diseases in a collaborative environment. A primary responsibility of the successful candidate will be to develop and execute complex neuronal models of Tau pathology with a focus on Alzheimer Disease. Experience with molecular and cellular biology, neuronal cell culture, microfluidic devices and confocal microscopy would be an asset. The position is offered for 2 years.

Key Objectives:

  • Designing disease-relevant assays and methods to support AbbVie’s contributions and efforts in the IMI project IMPRiND (Inhibiting Misfolded Protein Propagation in Neurodegenerative Disease).

  • Independently design, execute, analyze and interpret experiments to address key scientific questions.

  • Contribute to identify new targets, design and execute target validation studies.

  • Design, establish and validate neuronal models for Alzheimer Disease.

  • Identify, develop and optimize new techniques to address critical project needs.

  • Effectively compile and present scientific plans and data.

  • Read and apply relevant scientific literature to support scientific discussions.

  • Collaborate with other groups in discovery, developmental sciences and global colleagues.

Education and qualification:

  • PhD in neuroscience, cell biology or related fields with at least 2 years of postdoctoral or equivalent industrial experience. Experience in drug discovery would be an advantage.

  • Track-record in neurodegenerative diseases would be desirable.

  • Expertise in protein biochemistry, molecular and cellular biology, including method development and validation.

  • Expertise with culturing primary neurons and/or iPSC-derived neurons and their genetic manipulation.

  • Detailed knowledge on establishing neuronal models in microfluidic devices would be an advantage.

  • Very good skills in planning and coordination of complex interdisciplinary studies.

  • A high degree of self-initiative, independency, flexibility and curiosity.

  • Excellent teamwork and interpersonal relationship skills.

  • Good communication skills and proficiency in English (written and oral).

  • Ability to present scientific activities/results at internal and external meetings, and publish in peer-reviewed journals

We offer you:

  • A fantastic opportunity to work in in a world-class team.

  • A mentor who will assist you as coach and contact person.

  • A supportive environment that allows you to focus on your role and tailor your work to your individual needs, including flexible work models, multiple benefits, and comprehensive health and sports programs.

  • Attractive compensation and company benefits, including our excellent occupational health management system, which is one of the best in Germany.

Additional Information

  • Significant Work Activities and Conditions: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)

  • Travel: Yes, 5 % of the Time

  • Job Type: Experienced

  • Schedule: Full-time

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