AbbVie Post-Doctoral Research Scientist - Tau Biology, Neuroscience Discovery (m/w/d) in Ludwigshafen, Germany
Post-Doctoral Research Scientist - Tau Biology, Neuroscience Discovery (m/w/d)
Germany, Rhinland-Palatinate, Ludwigshafen
Research & Development
The position is located within the Tau Biology Group in the Neuroscience Discovery organization at Ludwigshafen and will support a European Innovative Medicines Initiative (IMI) Project. The accomplished neurobiologist will make substantial contributions to the conception and execution of new therapeutic approaches to neurodegenerative diseases in a collaborative environment. A primary responsibility of the successful candidate will be to develop and execute complex neuronal models of Tau pathology with a focus on Alzheimer Disease. Experience with molecular and cellular biology, neuronal cell culture, microfluidic devices and confocal microscopy would be an asset. The position is offered for 2 years.
Designing disease-relevant assays and methods to support AbbVie’s contributions and efforts in the IMI project IMPRiND (Inhibiting Misfolded Protein Propagation in Neurodegenerative Disease).
Independently design, execute, analyze and interpret experiments to address key scientific questions.
Contribute to identify new targets, design and execute target validation studies.
Design, establish and validate neuronal models for Alzheimer Disease.
Identify, develop and optimize new techniques to address critical project needs.
Effectively compile and present scientific plans and data.
Read and apply relevant scientific literature to support scientific discussions.
Collaborate with other groups in discovery, developmental sciences and global colleagues.
Education and qualification:
PhD in neuroscience, cell biology or related fields with at least 2 years of postdoctoral or equivalent industrial experience. Experience in drug discovery would be an advantage.
Track-record in neurodegenerative diseases would be desirable.
Expertise in protein biochemistry, molecular and cellular biology, including method development and validation.
Expertise with culturing primary neurons and/or iPSC-derived neurons and their genetic manipulation.
Detailed knowledge on establishing neuronal models in microfluidic devices would be an advantage.
Very good skills in planning and coordination of complex interdisciplinary studies.
A high degree of self-initiative, independency, flexibility and curiosity.
Excellent teamwork and interpersonal relationship skills.
Good communication skills and proficiency in English (written and oral).
Ability to present scientific activities/results at internal and external meetings, and publish in peer-reviewed journals
We offer you:
A fantastic opportunity to work in in a world-class team.
A mentor who will assist you as coach and contact person.
A supportive environment that allows you to focus on your role and tailor your work to your individual needs, including flexible work models, multiple benefits, and comprehensive health and sports programs.
Attractive compensation and company benefits, including our excellent occupational health management system, which is one of the best in Germany.
Significant Work Activities and Conditions: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: Yes, 5 % of the Time
Job Type: Experienced