AbbVie Senior Scientist II/III, Engineering in Lake County, Illinois
Senior Scientist II/III, Engineering
USA, Illinois, Lake County
Research & Development
Process Research and Development invents chemical processes and prepares active pharmaceutical ingredient (API) to enable clinical trials, toxicology studies and drug product development for AbbVie’s pre-clinical and clinical drug pipeline.
In addition to working with small molecules, Process R&D also develops antibody drug conjugates (ADC). We create valuable intellectual property through composition of matter, chemical processes and technologies resulting in cost effective commercial manufacturing processes. We develop the supply chain for APIs, prepare and defend CMC (Chemistry, Manufacturing and Control) regulatory content.
Chemical Engineers in AbbVie's R&D work in multi-functional teams to develop scalable processes and supply API for safety testing, clinical trials and formulation development. The teams include Process Chemistry, Pilot Plant Operations, Analytical Chemistry and Solid State Chemistry. Chemical Engineers support API projects through all phases of development. Early in development, engineers focus on ensuring the process can be run safely, identifying and addressing major scale-up issues and developing the final (API) process step.
Later in the development process, engineers optimize the API process and lead process campaigns run in the R&D Pilot Plant. In the final stage of development, engineers transfer the optimized process to manufacturing and support process validation.
The successful candidate will play a key role in the Process Chemical Engineering function within Process R&D.
Developrobust commercial processes to manufacture small molecule APIs and ADCs.
Address challenging problems in chemicalreactions, extractions, distillations, crystallizations, filtration and dryingto meet the target chemical and physical property attributes of the product throughan in-depth scientific assessment of these unit processes/operations.
Expected to lead identification and development of novel approachesand technologies to enhance efficiency in process development andcommercialization.
Must exhibit a collaborative nature inidentifying process challenges on a wide range of projects, and take on a leadershiprole in developing and implementing solutions.
Level and compensation will be commensurate with experience.
BS, MS, PhD in Chemical Engineering with 12+ (BS), 10+ (MS), or 4+ (PhD) years of experience
Strong background in the design and developmentof chemical engineering unit operations and processes.
Must possess at least 3 years of demonstrated pharmaceuticaldevelopment experience and familiarity with various process analyticaltechnologies (PATs).
BS, MS, PhD in Chemical Engineering with 14+ (BS), 12+ (MS), or 6+ (PhD) years of experience
Experience with laboratory experiments, process scale-up from lab to pilot plant and/or transferring a process from pilot plant to a commercial facility.
Experience working in an API Plant environment. Familiarity with operation of chemical process equipment and systems.
Strong technical background in chemical processing unit operations including reactions, crystallization, distillation, extraction, membrane separation, chromatography, centrifugation, filtration, drying and milling.
Key Leadership Competencies:
Builds strong relationships with peers and cross functionally with partners to enable higher performance.
Learns fast, grasps the "essence" and can change course quickly where indicated.
Raises the bar and is never satisfied with the status quo.
Creates a learning environment, open to suggestions and experimentation for improvement.
Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Strong interpersonal and communication skills with demonstrated ability to work within a team environment.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled