AbbVie Senior Scientist III, PAT in Lake County, Illinois
Senior Scientist III, PAT
USA, Illinois, Lake County
Research & Development
This Senior Scientist role is recognized to be an interdisciplinary effort between engineering, analytical, and formulation functions and will report through Analytical Research and Development (ARD). ARD scientists work in multi-functional teams to inform formulation and manufacturing process selection to advance projects through all phases of development.
The successful candidate will focus on PAT (Process Analytical Technology) implementation of on-line/in-line/at-line measurements during drug product manufacturing to inform formulation and process development efforts and assist in the determination of robust commercial control strategies through improved process understanding.
Additionally, the role will include a focus on PAT development, project management across functional boundaries, use of disparate equipment as well as accountability for software and infrastructure selection, deployment and maintenance.
Own the accountability for PAT installations including instrument selection, procurement, interfacing with processing equipment, maintenance, and application optimization
Develop and execute a plan to store, share and analyze multivariate process and analytical data to provide long-term value to process development and manufacturing teams
Collaboration with internal subject matter experts to deliver PAT methods (NIR,Raman, particle size) and data models to support manufacturing unit operations though collaborative efforts and individual technical contributions
Author and review technical documents, driving cross-site standardization efforts
Seek opportunities for innovative solutions, proactively addressing technical development challenges
Work with cross-functional teams to provide deeper understanding of properties/process/product performance relationships using appropriate PAT tools and models
Work closely with formulation scientists and process engineers on implementation of PAT tools including training and troubleshooting
Level of role will be based on education & years of experience
Bachelor’s Degree (and 12+ years of experience), Master’s Degree (and 10+ years of experience), or PhD (and 4+ years of experience) in Chemistry, Physical Sciences, Mathematics or Engineering required
Understanding of NIR, Raman, particle size and other measurement techniques that are suitable for inline/ at-line analysis
Understanding of processing equipment used in pharmaceutical drug product unit operations
Experience with statistics, chemometrics, and programming and data modeling packages such as Unscrambler
Excellent written and verbal communication skills
Direct experience in the development of PAT methods and data models, statistical data analysis and the evaluation of new on-line/at-line/in-line technologies to support drug product process development is highly desired
Pharmaceutical industry experience strongly preferred
Equal Opportunity Employer Minorities/Women/Veterans/Disabled