AbbVie Scientist I/II, Biotransformation in Lake County, Illinois

Scientist I/II, Biotransformation

USA, Illinois, Lake County

1 additional location

USA, Illinois

Research & Development

Requisition #1901803

The Biotransformation group in DMPK-BA is seeking a talented scientist to join our discovery metabolite ID team. The successful candidate will be responsible for providing analyticalsupport to discovery-stage projects across therapeutic areas. They will develop custom in vitro assays to support unique project issues, and optimize analytical methods to analyze novel compound chemistries. The candidate will collaborate across various disciplines within AbbVie including DMPK, chemistry, and biology to support biotransformation. The scientist will be the primary point of contact to the project teams


  • Independently design and conduct discovery-stagemetabolite ID experiments, including invitro incubations, sample preparation, data analysis, and report generation

  • Operate, maintain, and troubleshoot LC-MS/MSsystems

  • Develop and optimize analytical methods inresponse to changing chemical landscape

  • Communicate with project teams acrosstherapeutic areas

Level will be based on education & years of experience.


  • B.S. (and 5 years) or M.S. (and 3 years) in analytical chemistry,pharmacology, or related field with previous laboratory experience

  • Demonstrated experience with in vitro systems and LC-MS analysis

  • Excellent written and oral communication skills

  • Ability to work independently with minimalsupervision in managing multiple projects and priorities

  • Works well within a team


  • Experience with Thermo mass spectrometers(Orbitrap, Fusion, QExactive)

  • Knowledge of drug metabolism pathways andmetabolite ID data analysis

  • Familiarity with MassMetasite/WebMetabase

Key AbbVie Competencies:

  • Builds strong relationships with peers and crossfunctionally with partners outside of team

  • Learns fast, grasps the 'essence,' and canchange course quickly where indicated

  • Raises the bar and is never satisfied with thestatus quo

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

Additional Information

  • Significant Work Activities and Conditions: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)

  • Travel: Yes, 5 % of the Time

  • Job Type: Experienced

  • Schedule: Full-time