AbbVie 2019 Experiential Internship (Graduate Level) - Drug Metabolism and Pharmacokinetics/Bioanalysis Intern in Lake County, Illinois

2019 Experiential Internship (Graduate Level) - Drug Metabolism and Pharmacokinetics/Bioanalysis Intern

USA, Illinois, Lake County

New

Administrative Services

Requisition #1901981

Asan AbbVie Experiential Intern, you'll participate in a paid, ten to twelve-week summer program that is focused on providing students with robust projects throughout the summer. As an intern, you will be located at our corporate headquarters in north suburban Chicago, with housing and shuttle services for eligible students.

Department Overview – Drug Metabolism and Pharmacokinetics/Bioanalysis

With the framework of drug metabolism and pharmacokinetics, the department seeks to advance the pipeline and enhance probability of success with enabling science and innovation. We aim to deliver high quality, timely, cost-competitive data for decision making. We also strive to build a culture of trust and seamless collaboration with internal partners and expand our reach toward external collaborations.

Assignment Details

The project would involve investigation of in vitro methods to predict in vivo conversion of permeability (and possibly solubility-) enhancing pro-drugs. Working under supervision and closely with the bioanalytical group, the candidate would conduct experiments with small molecule pro-drugs, both commercially available and those from internal programs to assess in vitro metabolic stability and/or intrinsic clearance. The project would involve the use of various sources of carboxylesterases (intestinal microsomes, liver microsomes, recombinant enzymes). The ideal candidate would have the ability to analyze literature, summarize results and replicate experimental results. The outcome of this work is expected to make advances toward a larger overarching goal of better understanding of mechanistic modeling of absorption.

Basic:

  • Completed at least one year of college education before beginning internship

  • Must be enrolled in school the semester following your internship

  • Graduate Level Student in Pharmaceutical Sciences, Pharmacology, Toxicology

  • Minimum Cumulative GPA: 3.0/4.0

  • Must be authorized to work in the U.S. on a permanent basis without requiring sponsorship (students on an F1 visa with CPT can be accommodated).

Additional Information

  • AbbVie is an Equal Employment Opportunity employer: At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

  • Significant Work Activities and Conditions: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)

  • Travel: No

  • Job Type: Internship

  • Schedule: Full-time