AbbVie Senior Scientist I/II, In Vivo Pharmacology, Parkinson’s Disease in Cambridge, Massachusetts

Senior Scientist I/II, In Vivo Pharmacology, Parkinson’s Disease

USA, Massachusetts, Cambridge


1 additional location

USA, Massachusetts

Research & Development

Requisition #1901908

AbbVie is investing heavily in a new research enterprise in Cambridge, Boston - the Foundational Neuroscience Center (FNC). The FNC will investigate the fundamental biological mechanisms underpinning neurodegenerative disease, especially Alzheimer’s disease.

AbbVie is seeking an experienced, highly motivated, lab-based Senior Scientist with experience working with biologics and small molecules in preclinical models of Parkinson’s disease to join the FNC In Vivo Pharmacology team. The successful candidate will independently design and implement experiments to address target engagement, mechanisms-of-action and efficacy of therapeutic molecules.

Key Responsibilities Includes:

  • Design and interpret in vivo pharmacology studies to evaluate the activities of biologic drug candidates including PK/PD characteristics, target engagement, mechanisms of action and efficacy

  • Collaborate with keyinternal and external scientists to drive improved understanding of diseasepathophysiology and target biology

  • Overseeinteractions with contract research labs and academic institutions forpreclinical studies, including lab selection, protocol development, oversightand review of final report

  • Train and managedirect reports

Position will be hired based on level of experience.

  • PhD in Neuroscience or related field with 0-4+ years of academic or industry research experience; MS with 8-10+ years of experience; BS with 10-12+ years of experience.

  • Must have experience designing and conducting in vivo pharmacology studies with in animal models of Parkinson’s disease

  • Excellent in vivo skills (dosing, tissue/fluid harvest) and prior experience doing biochemical and/or histological analysis required

  • Experience in standard molecular biology and protein biochemistry techniques (e.g. protein purification, ELISA, WB) is also highly preferred

  • Outstanding organizational and critical thinking skills

  • Excellent verbal and written communication and interpersonal skills to work across functions and across sites, and within academic collaborations

Additional Information

  • AbbVie is an Equal Employment Opportunity employer: At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer, we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

  • Significant Work Activities and Conditions: N/A

  • Travel: Yes, 5 % of the Time

  • Job Type: Experienced

  • Schedule: Full-time